Gold-catalysed synthesis of amino acid-derived 2,5-disubstituted oxazoles

Christopher L. Paradise, Pooja R. Sarkar, Mina Razzak, Jef K. De Brabander

Research output: Contribution to journalArticlepeer-review

33 Scopus citations


Amino acid-derived propargylic amides are cyclised in a one-pot, Au(iii)-catalysed operation to yield 5-bromomethyl oxazoles. These compounds are further elaborated to bis-heterocycles, dipeptide mimics and more.

Original languageEnglish (US)
Pages (from-to)4017-4020
Number of pages4
JournalOrganic and Biomolecular Chemistry
Issue number11
StatePublished - Jun 7 2011

ASJC Scopus subject areas

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry


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