Genetic Influences on Pediatric AKI

Kathy Lee-Son; Massimo Attanasio

doi:10.1007/978-981-33-4554-6_13

Genetic Influences on Pediatric AKI

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

Pediatric acute kidney injury is becoming a widely recognized clinical diagnosis that can be found across the clinical spectrum. The advances of genomic studies in the field of nephrology, specifically the pathophysiology mechanisms of ischemia-reperfusion, sepsis, and nephrotoxicity as they relate to acute kidney injury, have stimulated the desire to understand a genotype-phenotype connection. Ranging from targeted gene to genome-wide association studies, acute kidney injury genetic study designs warrant thoughtful methodology considerations in order to minimize bias and to improve result validity.

Original language	English (US)
Title of host publication	Advances in Critical Care Pediatric Nephrology
Subtitle of host publication	Point of Care Ultrasound and Diagnostics
Publisher	Springer Singapore
Pages	123-131
Number of pages	9
ISBN (Electronic)	9789813345546
ISBN (Print)	9789813345539
DOIs	https://doi.org/10.1007/978-981-33-4554-6_13
State	Published - Jan 1 2021
Externally published	Yes

Keywords

Acute kidney injury
Genetic
Genetic association studies
Pediatric

ASJC Scopus subject areas

General Medicine
General Biochemistry, Genetics and Molecular Biology

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10.1007/978-981-33-4554-6_13

Cite this

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Genetic Influences on Pediatric AKI

Abstract

Keywords

ASJC Scopus subject areas

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