Gene regulation: Protein escorts to the transcription ball

J. W. Chin; J. J. Kohler; T. L. Schneider; A. Schepartz

doi:10.1016/S0960-9822(00)80107-4

Gene regulation: Protein escorts to the transcription ball

J. W. Chin, J. J. Kohler, T. L. Schneider, A. Schepartz

Research output: Contribution to journal › Comment/debate › peer-review

2 Scopus citations

Abstract

A new way by which the potency of a eukaryotic transcription factor can be regulated has been discovered, in which nuclear factors increase the concentration of the transcription factor's active form by modulating an otherwise unfavorable equilibrium between monomeric and dimeric forms of the protein.

Original language	English (US)
Pages (from-to)	R929-R932
Journal	Current Biology
Volume	9
Issue number	24
DOIs	https://doi.org/10.1016/S0960-9822(00)80107-4
State	Published - Dec 16 1999

ASJC Scopus subject areas

Biochemistry, Genetics and Molecular Biology(all)
Agricultural and Biological Sciences(all)

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10.1016/S0960-9822(00)80107-4

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title = "Gene regulation: Protein escorts to the transcription ball",

abstract = "A new way by which the potency of a eukaryotic transcription factor can be regulated has been discovered, in which nuclear factors increase the concentration of the transcription factor's active form by modulating an otherwise unfavorable equilibrium between monomeric and dimeric forms of the protein.",

author = "Chin, {J. W.} and Kohler, {J. J.} and Schneider, {T. L.} and A. Schepartz",

note = "Funding Information: Thanks to the Medicinal and Organic Divisions of the American Chemical Society for predoctoral fellowships to J.J.K. and T.L.S., respectively, and to the Arthur Wayland Dox Foundation and the US-UK Fulbright Commission for a predoctoral fellowship to J.W.C. Research in the authors{\textquoteright} laboratory is supported by grants from the NIH. ",

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T1 - Gene regulation

T2 - Protein escorts to the transcription ball

AU - Chin, J. W.

AU - Kohler, J. J.

AU - Schneider, T. L.

AU - Schepartz, A.

N1 - Funding Information: Thanks to the Medicinal and Organic Divisions of the American Chemical Society for predoctoral fellowships to J.J.K. and T.L.S., respectively, and to the Arthur Wayland Dox Foundation and the US-UK Fulbright Commission for a predoctoral fellowship to J.W.C. Research in the authors’ laboratory is supported by grants from the NIH.

PY - 1999/12/16

Y1 - 1999/12/16

N2 - A new way by which the potency of a eukaryotic transcription factor can be regulated has been discovered, in which nuclear factors increase the concentration of the transcription factor's active form by modulating an otherwise unfavorable equilibrium between monomeric and dimeric forms of the protein.

AB - A new way by which the potency of a eukaryotic transcription factor can be regulated has been discovered, in which nuclear factors increase the concentration of the transcription factor's active form by modulating an otherwise unfavorable equilibrium between monomeric and dimeric forms of the protein.

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VL - 9

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JO - Current Biology

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Gene regulation: Protein escorts to the transcription ball

Abstract

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