Future applications of DWI in MS

Joseph A. Maldjian, Robert I. Grossman

Research output: Contribution to journalArticlepeer-review

20 Scopus citations


Diffusion imaging is a noninvasive technique for measuring the movement of water molecules. Although it has had its greatest impact thus far in the area of stroke imaging, the information garnered from diffusion experiments can provide an indication of myelin injury and perhaps axonal integrity. In this paper, we describe some current and potential future applications of diffusion imaging in multiple sclerosis. These include the use of global indices such as diffusion trace and anisotropy, as well as implementation of axonal fiber tracking methodologies for assessment of axonal integrity and connectivity between cortical regions.

Original languageEnglish (US)
Pages (from-to)S55-S57
JournalJournal of the Neurological Sciences
Issue numberSUPPL. 1
StatePublished - May 1 2001


  • Diffusion imaging
  • Magnetic resonance
  • Multiple sclerosis

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology


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