Funkční MR zobrazení mozkové aktivace při testu verbální fluence u pacientů s patologií levé hemisféry: Součást předoperačního plánování

Translated title of the contribution: Presurgical fMRI of verbal processing

Jaroslav Tintěra, J. Klener, J. Horáček, F. Španiel, R. Chabiniok, P. Kršek, J. Vymazal

Research output: Contribution to journalArticlepeer-review


Functional magnetic resonance imaging (fMRI) was used for pre-surgical mapping of brain verbal processing in patients suffering from left hemisphere lesion. A file of patients contained 20 subjects divided into two groups according to age: the group of young patients of 9-21 years and the group of older patients of 29-72 years. A word generation with the verbal fluency test was used to stimulate brain verbal areas. Functional activations were qualitatively compared with standard functional maps measured on the group of healthy volunteers. These standard maps showed 3 main clusters of active voxels in the left hemisphere (a group statistic was performed in both 10 right-hander subjects and separately in 5 left-hander subjects). Authors found higher number of bilaterally activated clusters and also of complete inter-hemispherical shift in patients with left hemisphere lesion compared to normal population. In the group of young patients, there were 33% of bilateral activations found in some of 3 standard functional locations and in 8% even complete shift to the right hemisphere was observed. Some bilateral activation was found only in 17% in the group of older subjects. This study confirms higher probability of bilateral verbal activation or even shift of activity from the left to the right hemisphere in young patients at least in some participating verbal area.

Translated title of the contributionPresurgical fMRI of verbal processing
Original languageCzech
Pages (from-to)8-14
Number of pages7
JournalCeska Radiologie
Issue number1
StatePublished - 2004
Externally publishedYes


  • Language
  • Reorganization
  • Surgery
  • Verbal fluency
  • fMRI

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging


Dive into the research topics of 'Presurgical fMRI of verbal processing: Součást předoperačního plánování'. Together they form a unique fingerprint.

Cite this