From small pelvic outlet syndrome to sirenomelia

Guido Currarino, Arthur Weinberg

Research output: Contribution to journalArticlepeer-review

15 Scopus citations


We report 5 newborns with a contracted lesser pelvis, imperforate anus (severely stenotic and ectopic anus in 1 case), absent or rudimentary urinary tract, and defective or absent external genitalia, vagina, and uterus but normal gonads. The first 2 patients had small pelvic outlet syndrome (SPOS). The findings in the third patient, a possible transition to sirenomelia, were more severe and included malposition of the penis to the posterior sacral area. The fourth and fifth patients had sirenomelia. The remarkable similarity of many abnormalities observed in these cases and related material in the literature suggests that SPOS and sirenomelia may be part of the same malformation complex (SPOS/sirenomelia complex)..

Original languageEnglish (US)
Pages (from-to)195-210
Number of pages16
JournalFetal and Pediatric Pathology
Issue number2
StatePublished - Jan 1 1991


  • Anus
  • Caudal regression
  • External genitalia
  • Pelvis
  • Sirenomelia
  • Urinary tract

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Pathology and Forensic Medicine


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