Food Allergy Immunotherapy with Adjuvants

Research output: Contribution to journalReview articlepeer-review

14 Scopus citations

Abstract

Treatment of immunoglobulin E–mediated food allergy has traditionally been limited to allergen avoidance and emergency treatment after accidental ingestion. In recent years, significant progress has been made with oral, sublingual, and epicutaneous immunotherapy in the treatment of food allergy; however, these emerging treatment options have important limitations in efficacy, durability of effect, and safety. These limitations have already spurred interest in the development of adjuvant therapies to increase efficacy, produce more durable immunologic changes, and/or reduce treatment-related adverse reactions.

Original languageEnglish (US)
Pages (from-to)149-173
Number of pages25
JournalImmunology and Allergy Clinics of North America
Volume40
Issue number1
DOIs
StatePublished - Feb 2020

Keywords

  • Adjuvant therapy
  • EPIT
  • Food allergy
  • Modified allergens
  • OIT
  • SLIT

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology

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