Abstract
The ongoing coronavirus disease 2019 pandemic has resulted in additional challenges for systems designed to perform expeditious primary percutaneous coronary intervention for patients presenting with ST-segment-elevation myocardial infarction. There are 2 important considerations: the guideline-recommended time goals were difficult to achieve for many patients in high-income countries even before the pandemic, and there is a steep increase in mortality when primary percutaneous coronary intervention cannot be delivered in a timely fashion. Although the use of fibrinolytic therapy has progressively decreased over the last several decades in high-income countries, in circumstances when delays in timely delivery of primary percutaneous coronary intervention are expected, a modern fibrinolytic-based pharmacoinvasive strategy may need to be considered. The purpose of this review is to systematically discuss the contemporary role of an evidence-based fibrinolytic reperfusion strategy as part of a pharmacoinvasive approach, in the context of the emerging coronavirus disease 2019 pandemic.
Original language | English (US) |
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Pages (from-to) | E009622 |
Journal | Circulation: Cardiovascular Interventions |
Volume | 13 |
Issue number | 9 |
DOIs | |
State | Published - Sep 1 2020 |
Keywords
- coronavirus
- fibrinolysis
- myocardial infarction
- pandemic
- reperfusion
ASJC Scopus subject areas
- Cardiology and Cardiovascular Medicine