Feasibility of MRI-guided transurethral thermal therapy for prostate cancer

R. Chopra, M. Burtnyk, S. N. Baker, V. Choy, S. Lochhead, M. J. Bronskill

Research output: Chapter in Book/Report/Conference proceedingConference contribution


A control algorithm has been developed for MRI-guided conformal thermal therapy of the prostate gland with transurethral ultrasound heating applicators. The ability of the algorithm to produce conformal thermal damage patterns was evaluated using prostate boundaries obtained from clinical MR images and Bioheat Transfer simulations of the heating process. The algorithm enabled the generation of conformal thermal damage patterns with an error of less than 3mm across eleven prostates. Treatment times ranged from 12-45 minutes depending on prostate size. Rectal cooling may be important in protecting the rectal wall from unwanted thermal damage.

Original languageEnglish (US)
Title of host publicationProceedings - IEEE Ultrasonics Symposium
EditorsM.P. Yuhas
Number of pages3
StatePublished - 2004
Event2004 IEEE Ultrasonics Symposium - Montreal, Que., Canada
Duration: Aug 23 2004Aug 27 2004


Other2004 IEEE Ultrasonics Symposium
CityMontreal, Que.


  • BHTE
  • HIFU
  • Image-guided therapy
  • MRI
  • Prostate cancer
  • Thermal therapy
  • Ultrasound

ASJC Scopus subject areas

  • Engineering(all)


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