Fatty Acid Desaturation Gets a NAD                         +                          Reputation

Andrew J. Lutkewitte; Shawn C. Burgess; Brian N. Finck

doi:10.1016/j.cmet.2019.03.007

Fatty Acid Desaturation Gets a NAD ⁺ Reputation

Andrew J. Lutkewitte, Shawn C. Burgess, Brian N. Finck

Research output: Contribution to journal › Short survey › peer-review

4 Scopus citations

Abstract

delta-5 desaturase and delta-6 desaturase are enzymes known to be involved in the synthesis of highly unsaturated fatty acids. In this issue, Kim et al. (2019) show that production of NAD ⁺ by this desaturase reaction is an adaptive response to NAD ⁺ depletion that may regulate cellular REDOX status.

Original language	English (US)
Pages (from-to)	790-792
Number of pages	3
Journal	Cell Metabolism
Volume	29
Issue number	4
DOIs	https://doi.org/10.1016/j.cmet.2019.03.007
State	Published - Apr 2 2019

ASJC Scopus subject areas

Physiology
Molecular Biology
Cell Biology

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10.1016/j.cmet.2019.03.007

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title = " Fatty Acid Desaturation Gets a NAD + Reputation ",

abstract = " delta-5 desaturase and delta-6 desaturase are enzymes known to be involved in the synthesis of highly unsaturated fatty acids. In this issue, Kim et al. (2019) show that production of NAD + by this desaturase reaction is an adaptive response to NAD + depletion that may regulate cellular REDOX status.",

author = "Lutkewitte, {Andrew J.} and Burgess, {Shawn C.} and Finck, {Brian N.}",

note = "Publisher Copyright: {\textcopyright} 2019 Elsevier Inc.",

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AU - Lutkewitte, Andrew J.

AU - Burgess, Shawn C.

AU - Finck, Brian N.

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AB - delta-5 desaturase and delta-6 desaturase are enzymes known to be involved in the synthesis of highly unsaturated fatty acids. In this issue, Kim et al. (2019) show that production of NAD + by this desaturase reaction is an adaptive response to NAD + depletion that may regulate cellular REDOX status.

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SP - 790

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JO - Cell Metabolism

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Fatty Acid Desaturation Gets a NAD ⁺ Reputation

Abstract

ASJC Scopus subject areas

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