Abstract
A method to quickly modify a treatment plan in adaptive radiotherapy was proposed and studied. The method is based on a Cimmino-type algorithm in linear programming. The fast convergence speed is achieved by over-relaxing the algorithm relaxation parameter from its sufficient convergence range of (0, 2) to (0, ∞). The algorithm parameters are selected so that the over-relaxed Cimmino (ORC) algorithm can effectively approximate an unconstrained re-optimization process in adaptive radiotherapy. To demonstrate the effectiveness and flexibility of the proposed method in adaptive radiotherapy, two scenarios with different organ motion/deformation of one nasopharyngeal case were presented with comparisons made between this method and the re-optimization method. In both scenarios, the ORC algorithm modified treatment plans have dose distributions that are similar to those given by the re-optimized treatment plans. It takes us using the ORC algorithm to finish a treatment plan modification at least three times faster than the re-optimization procedure compared.
Original language | English (US) |
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Pages (from-to) | 191-200 |
Number of pages | 10 |
Journal | Medical physics |
Volume | 31 |
Issue number | 2 |
DOIs | |
State | Published - Feb 2004 |
Keywords
- Adaptive radiotherapy
- Cimmino
- Optimization
- Treatment plan modification
ASJC Scopus subject areas
- Biophysics
- Radiology Nuclear Medicine and imaging