Fast Monte Carlo estimation of patient and detector scatter and crosstalk contamination in SPECT imaging

Jinsong Ouyang, Stephen C. Moore, Mi Ae Park, Georges El Fakhri

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2 Scopus citations


Monte Carlo methods offer the potential to provide an accurate correction for scatter and detector effects, especially when imaging isotopes that emit multiple photons, or dual-isotopes. Recently, a group at Utrecht University has developed some promising acceleration techniques by combining scatter maps with convolution-based forced detection. We extend their work in four ways: using the Delta Scattering technique to rapidly determine photon interaction points, simulating scatter maps for many energy bins to improve accuracy, decoupling the simulation of the object and the detector using point spread functions which include all detector effects, and including coherent scattering in addition to photoelectric effect and Compton scattering when simulating photon interactions. We store point spread functions as multi-dimensional arrays to improve speed and accuracy. A software package was developed and validated in a torso phantom experiment. Three spheres filled with 111In were placed in the non-uniformly attenuating phantom. CT and SPECT scans were acquired and spatially registered. A good agreement between experimental and simulated profiles was found for four energy windows (50-95, 81-104, 147-195, 212-278 keV). For the two low energy windows, primary photons contribution can be modeled correctly only if the PSF includes all detector effects. A triple-energy window method overestimated scatter profiles compared to the Monte Carlo simulated scatter.

Original languageEnglish (US)
Title of host publication2005 IEEE Nuclear Science Symposium Conference Record -Nuclear Science Symposium and Medical Imaging Conference
Number of pages3
StatePublished - 2005
Externally publishedYes
EventNuclear Science Symposium Conference Record, 2005 IEEE - , Puerto Rico
Duration: Oct 23 2005Oct 29 2005

Publication series

NameIEEE Nuclear Science Symposium Conference Record
ISSN (Print)1095-7863


OtherNuclear Science Symposium Conference Record, 2005 IEEE
Country/TerritoryPuerto Rico

ASJC Scopus subject areas

  • Radiation
  • Nuclear and High Energy Physics
  • Radiology Nuclear Medicine and imaging


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