Fast imaging of phosphocreatine using a RARE pulse sequence

Robert L. Greenman; Mark A. Elliott; Krista Vandenborne; Mitchell D. Schnall; Robert E. Lenkinski

doi:10.1002/mrm.1910390523

Fast imaging of phosphocreatine using a RARE pulse sequence

Robert L. Greenman, Mark A. Elliott, Krista Vandenborne, Mitchell D. Schnall, Robert E. Lenkinski

Research output: Contribution to journal › Article › peer-review

25 Scopus citations

Abstract

A technique is described for acquiring phosphocreatine (PCr) images of skeletal muscle using a rapid acquisition with relaxation enhancement (RARE) pulse sequence. All of the phosphorus metabolites other than PCr are forced to dephase within the first few echoes, whereas the Carr-Purcell Meiboom- Gill (CPMG) pulse sequence maintains a high PCr signal long enough to acquire 64 echoes in a single shot. Axial PCr images of a human forearm with a signal-to-noise ratio of 9 were acquired in 2 min. The effect of the refocusing pulse seotion profile on the ratio of desired to undesired metabolite signal is demonstrated.

Original language	English (US)
Pages (from-to)	851-854
Number of pages	4
Journal	Magnetic resonance in medicine
Volume	39
Issue number	5
DOIs	https://doi.org/10.1002/mrm.1910390523
State	Published - May 1998

Keywords

Multiecho sequence
Phosphorus Imaging
RARE

ASJC Scopus subject areas

Radiology Nuclear Medicine and imaging

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10.1002/mrm.1910390523

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title = "Fast imaging of phosphocreatine using a RARE pulse sequence",

abstract = "A technique is described for acquiring phosphocreatine (PCr) images of skeletal muscle using a rapid acquisition with relaxation enhancement (RARE) pulse sequence. All of the phosphorus metabolites other than PCr are forced to dephase within the first few echoes, whereas the Carr-Purcell Meiboom- Gill (CPMG) pulse sequence maintains a high PCr signal long enough to acquire 64 echoes in a single shot. Axial PCr images of a human forearm with a signal-to-noise ratio of 9 were acquired in 2 min. The effect of the refocusing pulse seotion profile on the ratio of desired to undesired metabolite signal is demonstrated.",

keywords = "Multiecho sequence, Phosphorus Imaging, RARE",

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year = "1998",

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doi = "10.1002/mrm.1910390523",

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T1 - Fast imaging of phosphocreatine using a RARE pulse sequence

AU - Greenman, Robert L.

AU - Elliott, Mark A.

AU - Vandenborne, Krista

AU - Schnall, Mitchell D.

AU - Lenkinski, Robert E.

PY - 1998/5

Y1 - 1998/5

N2 - A technique is described for acquiring phosphocreatine (PCr) images of skeletal muscle using a rapid acquisition with relaxation enhancement (RARE) pulse sequence. All of the phosphorus metabolites other than PCr are forced to dephase within the first few echoes, whereas the Carr-Purcell Meiboom- Gill (CPMG) pulse sequence maintains a high PCr signal long enough to acquire 64 echoes in a single shot. Axial PCr images of a human forearm with a signal-to-noise ratio of 9 were acquired in 2 min. The effect of the refocusing pulse seotion profile on the ratio of desired to undesired metabolite signal is demonstrated.

AB - A technique is described for acquiring phosphocreatine (PCr) images of skeletal muscle using a rapid acquisition with relaxation enhancement (RARE) pulse sequence. All of the phosphorus metabolites other than PCr are forced to dephase within the first few echoes, whereas the Carr-Purcell Meiboom- Gill (CPMG) pulse sequence maintains a high PCr signal long enough to acquire 64 echoes in a single shot. Axial PCr images of a human forearm with a signal-to-noise ratio of 9 were acquired in 2 min. The effect of the refocusing pulse seotion profile on the ratio of desired to undesired metabolite signal is demonstrated.

KW - Multiecho sequence

KW - Phosphorus Imaging

KW - RARE

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JO - Magnetic resonance in medicine

JF - Magnetic resonance in medicine

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Fast imaging of phosphocreatine using a RARE pulse sequence

Abstract

Keywords

ASJC Scopus subject areas

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