Familial absorptive hypercalciuria in a large kindred

C. Y C Pak, J. McGuire, R. Peterson, F. Britton, M. J. Harrod

Research output: Contribution to journalArticlepeer-review

30 Scopus citations


The occurrence of calcareous renal stones in 12 members of a family was consistent with an autosomal dominant mode of inheritance. All 6 members with stones who were evaluated were shown to have absorptive hypercalciuria. The mother of two members with stones did not suffer but had biochemical evidence of absorptive hypercalciuria (increased intestinal calcium absorption, hypercalciuria and normal parathyroid function). Nephrolithiasis was encountered only in the progeny of members who had stones or biochemical absorptive hypercalciuria. The results suggest that physiological feature(s) of absorptive hypercalciuria may be an expression of the genetic trait.

Original languageEnglish (US)
Pages (from-to)717-719
Number of pages3
JournalUnknown Journal
Issue number6
StatePublished - 1981

ASJC Scopus subject areas

  • Urology


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