Expression of two myogenic regulatory factors myogenin and MyoDl during mouse embryogenesis

David Sassoon; Gary Lyons; Woodring E. Wright; Victor Lin; Andrew Lassar; Harold Weintraub; Margaret Buckingham

doi:10.1038/341303a0

Expression of two myogenic regulatory factors myogenin and MyoDl during mouse embryogenesis

David Sassoon, Gary Lyons, Woodring E. Wright, Victor Lin, Andrew Lassar, Harold Weintraub, Margaret Buckingham

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Abstract

MyoDl and myogenin are muscle-specific proteins which can convert non-myogenic cells in culture to differentiated muscle fibres, implicating them in myogenic determination. The pattern of expression of MyoDl and myogenin during the early stages of muscle formation in the mouse embryo in vivo and in limb-bud explants cultured in vitro, indicates that they may have different functions in different types of muscle during development.

Original language	English (US)
Pages (from-to)	303-307
Number of pages	5
Journal	Nature
Volume	341
Issue number	6240
DOIs	https://doi.org/10.1038/341303a0
State	Published - 1989

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title = "Expression of two myogenic regulatory factors myogenin and MyoDl during mouse embryogenesis",

abstract = "MyoDl and myogenin are muscle-specific proteins which can convert non-myogenic cells in culture to differentiated muscle fibres, implicating them in myogenic determination. The pattern of expression of MyoDl and myogenin during the early stages of muscle formation in the mouse embryo in vivo and in limb-bud explants cultured in vitro, indicates that they may have different functions in different types of muscle during development.",

author = "David Sassoon and Gary Lyons and Wright, {Woodring E.} and Victor Lin and Andrew Lassar and Harold Weintraub and Margaret Buckingham",

year = "1989",

doi = "10.1038/341303a0",

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T1 - Expression of two myogenic regulatory factors myogenin and MyoDl during mouse embryogenesis

AU - Sassoon, David

AU - Lyons, Gary

AU - Wright, Woodring E.

AU - Lin, Victor

AU - Lassar, Andrew

AU - Weintraub, Harold

AU - Buckingham, Margaret

PY - 1989

Y1 - 1989

N2 - MyoDl and myogenin are muscle-specific proteins which can convert non-myogenic cells in culture to differentiated muscle fibres, implicating them in myogenic determination. The pattern of expression of MyoDl and myogenin during the early stages of muscle formation in the mouse embryo in vivo and in limb-bud explants cultured in vitro, indicates that they may have different functions in different types of muscle during development.

AB - MyoDl and myogenin are muscle-specific proteins which can convert non-myogenic cells in culture to differentiated muscle fibres, implicating them in myogenic determination. The pattern of expression of MyoDl and myogenin during the early stages of muscle formation in the mouse embryo in vivo and in limb-bud explants cultured in vitro, indicates that they may have different functions in different types of muscle during development.

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ER -

Expression of two myogenic regulatory factors myogenin and MyoDl during mouse embryogenesis

Abstract

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