@article{36e5deeb633b412a84c2c8b17c7d4222,
title = "Expansion of TAVR into Low-Risk Patients and Who to Consider for SAVR",
abstract = "Transcatheter aortic valve replacement (TAVR) has revolutionized the treatment of severe aortic stenosis (AS) over the last decade. The results of the Placement of Aortic Transcatheter Valves (PARTNER) 3 and Evolut Low Risk trials demonstrated the safety and efficacy of TAVR in low-surgical-risk patients and led to the approval of TAVR for use across the risk spectrum. Heart teams around the world will now be faced with evaluating a deluge of younger, healthier patients with severe AS. Prior to the PARTNER 3 and Evolut Low Risk studies, this heterogenous patient population would have undergone surgical aortic valve replacement (SAVR). It is unlikely that TAVR will completely supplant SAVR for the treatment of severe AS in patients with a low surgical risk, as SAVR has excellent short- and long-term outcomes and years of durability data. In this review, we outline the critical role that SAVR will continue to play in the treatment of severe AS in the post-PARTNER 3/Evolut Low Risk era.",
keywords = "Aortic stenosis, Low risk, SAVR, TAVR",
author = "Patel, {Kunal V.} and Wally Omar and Gonzalez, {Pedro Engel} and Jessen, {Michael E.} and Lynn Huffman and Kumbhani, {Dharam J.} and Bavry, {Anthony A.}",
note = "Funding Information: No funding or sponsorship was received for this study or publication of this article. All named authors meet the International Committee of Medical Journal Editors (ICMJE) criteria for authorship for this article, take responsibility for the integrity of the work as a whole, and have given their approval for this version to be published. Kunal V. Patel, Wally Omar, Pedro Engel Gonzalez, Michael E. Jessen, Lynn Huffman, and Dharam J. Kumbhani have nothing to disclose. Anthony A. Bavry is a member of the journal{\textquoteright}s editorial board. This article is based on previously conducted studies and does not contain any studies with human participants or animals performed by any of the authors. Data sharing is not applicable to this article as no datasets were generated or analyzed during the current study. This article is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License, which permits any non-commercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by-nc/4.0/. Publisher Copyright: {\textcopyright} 2020, The Author(s).",
year = "2020",
month = dec,
day = "1",
doi = "10.1007/s40119-020-00198-z",
language = "English (US)",
volume = "9",
pages = "377--394",
journal = "Cardiology and Therapy",
issn = "2193-8261",
publisher = "Adis",
number = "2",
}