Evolution of coronary computed tomography radiation dose reduction at a tertiary referral center

Brian Burns Ghoshhajra, Leif Christopher Engel, Gyöngyi Petra Major, Alexander Goehler, Tust Techasith, Daniel Verdini, Synho Do, Bob Liu, Xinhua Li, Michiel Sala, Mi Sung Kim, Ron Blankstein, Priyanka Prakash, Manavjot S. Sidhu, Erin Corsini, Dahlia Banerji, David Wu, Suhny Abbara, Quynh Truong, Thomas J. BradyUdo Hoffmann, Manudeep Kalra

Research output: Contribution to journalArticlepeer-review

37 Scopus citations


Purpose: We aimed to assess the temporal change in radiation doses from coronary computed tomography angiography (CCTA) during a 6-year period. High CCTA radiation doses have been reduced by multiple technologies that, if used appropriately, can decrease exposures significantly. Methods: A total of 1277 examinations performed from 2005 to 2010 were included. Univariate and multivariable regression analysis of patient- and scan-related variables was performed with estimated radiation dose as the main outcome measure. Results: Median doses decreased by 74.8% (P <.001), from 13.1 millisieverts (mSv) (interquartile range 9.3-14.7) in period 1 to 3.3 mSv (1.8-6.7) in period 4. Factors associated with greatest dose reductions (P <.001) were all most frequently applied in period 4: axial-sequential acquisition (univariate: -8.0 mSv [-9.7 to -7.9]), high-pitch helical acquisition (univariate: -8.8 mSv [-9.3 to -7.9]), reduced tube voltage (100 vs 120 kV) (univariate: -6.4 mSv [-7.4 to -5.4]), and use of automatic exposure control (univariate: -5.3 mSv [-6.2 to -4.4]). Conclusions: CCTA radiation doses were reduced 74.8% through increasing use of dose-saving measures and evolving scanner technology.

Original languageEnglish (US)
Pages (from-to)764-772
Number of pages9
JournalAmerican Journal of Medicine
Issue number8
StatePublished - Aug 2012


  • Cardiac computed tomography
  • Coronary artery disease
  • Dose-savings methods
  • Radiation dose
  • Scan protocols

ASJC Scopus subject areas

  • Medicine(all)


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