Evidence-based medicine, part 6. An introduction to critical appraisal of clinical practice guidelines

Brent W. Sanderlin, Nashila AbdulRahim

Research output: Contribution to journalReview articlepeer-review

5 Scopus citations


This article provides an introductory step-by-step process to appraise clinical practice guidelines. The authors introduce these principles using a systematic approach and case-based format. The process of assessing the validity of clinical practice guidelines, determining their importance, and applying them to an individual patient is reviewed. The concepts of study population homogeneity, equal treatment, and study completeness are discussed to help physicians determine the validity of clinical practice guidelines. Finally, information that is learned from the previously mentioned steps is applied to patient care. Study generalizability and the role of patient values, expectations, and concerns are also addressed. The skills learned from appraising clinical practice guidelines in the manner outlined provides a solid basis for life-long learning and improved patient care.

Original languageEnglish (US)
Pages (from-to)321-324
Number of pages4
JournalJournal of the American Osteopathic Association
Issue number8
StatePublished - Aug 2007
Externally publishedYes

ASJC Scopus subject areas

  • Complementary and alternative medicine


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