Estimating cardiac fiber orientations in pig hearts using registered ultrasound and MR image volumes

James D. Dormer, Yuguang Meng, Xiaodong Zhang, Rong Jiang, Mary B. Wagner, Baowei Fei

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2 Scopus citations


Heart fiber mechanics can be important predictors in current and future cardiac function. Accurate knowledge of these mechanics could enable cardiologists to provide a diagnosis before conditions progress. Magnetic resonance diffusion tensor imaging (MR-DTI) has been used to determine cardiac fiber orientations. Ultrasound is capable of providing anatomical information in real time, enabling a physician to quickly adjust parameters to optimize image scans. If known fiber orientations from a template heart measured using DTI can be accurately deformed onto a cardiac ultrasound volume, fiber orientations could be estimated for the patient without the need for a costly MR scan while still providing cardiologists valuable information about the heart mechanics. In this study, we apply the method to pig hearts, which are a close representation of human heart anatomy. Experiments from pig hearts show that the registration method achieved an average Dice similarity coefficient (DSC) of 0.819 ± 0.050 between the ultrasound and deformed MR volumes and that the proposed ultrasound-based method is able to estimate the cardiac fiber orientation in pig hearts.

Original languageEnglish (US)
Title of host publicationMedical Imaging 2017
Subtitle of host publicationUltrasonic Imaging and Tomography
EditorsNeb Duric, Neb Duric, Brecht Heyde
ISBN (Electronic)9781510607231
StatePublished - 2017
Externally publishedYes
EventMedical Imaging 2017: Ultrasonic Imaging and Tomography - Orlando, United States
Duration: Feb 15 2017Feb 16 2017

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
ISSN (Print)1605-7422


ConferenceMedical Imaging 2017: Ultrasonic Imaging and Tomography
Country/TerritoryUnited States


  • Magnetic resonance diffusion tensor imaging (MR-DTI)
  • cardiac fiber imaging.
  • cardiac fiber orientation
  • deformable registration
  • heart disease
  • image registration
  • ultrasound imaging

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Biomaterials
  • Atomic and Molecular Physics, and Optics
  • Radiology Nuclear Medicine and imaging


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