Environment versus genetics in autoimmunity: A geneticist's perspective

Chandra Mohan

Research output: Contribution to journalArticlepeer-review

13 Scopus citations


Both environmental as well as genetic factors have been documented to contribute to autoimmunity, as is evident from the accompanying articles in this journal. This raises an important question-which of these two elements plays a more important role in the genesis of autoimmunity? This report encapsulates a geneticist's perspective on this interesting question. Though lupus is used as an example in this essay, the proposed model is envisaged to operate in other autoimmune diseases as well.

Original languageEnglish (US)
Pages (from-to)791-793
Number of pages3
Issue number11
StatePublished - 2006


  • Anti-DNA
  • Environment
  • Hormones
  • Nephritis
  • Qenetics
  • Sle loci

ASJC Scopus subject areas

  • Rheumatology


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