@article{5965ad4f51a549fa9e36d2aad73efb53,
title = "Ensuring due process in the IACUC and animal welfare setting: Considerations in developing noncompliance policies and procedures for institutional animal care and use committees and institutional officials",
abstract = "Every institution that is involved in research with animals is expected to have in place policies and procedures for the management of allegations of noncompliance with the Animal Welfare Act and the U.S. Public Health Service Policy on the Humane Care and Use of Laboratory Animals. We present here a model set of recommendations for institutional animal care and use committees and institutional officials to ensure appropriate consideration of allegations of noncompliance with federal Animal Welfare Act regulations that carry a significant risk or specific threat to animal welfare. This guidance has 3 overarching aims: 1) protecting the welfare of research animals; 2) according fair treatment and due process to an individual accused of noncompliance; and 3) ensuring compliance with federal regulations. Through this guidance, the present work seeks to advance the cause of scientific integrity, animal welfare, and the public trust while recognizing and supporting the critical importance of animal research for the betterment of the health of both humans and animals.",
keywords = "AWA, Humane animal care, OLAW, PHS",
author = "Hansen, {Barbara C.} and Sylvia Gografe and Stacy Pritt and Jen, {Kai lin Catherine} and McWhirter, {Camille A.} and Barman, {Susan M.} and Anthony Comuzzie and Molly Greene and McNulty, {Justin A.} and Michele, {Daniel Eugene} and Naz Moaddab and Nelson, {Randall J.} and Karen Norris and Uray, {Karen D.} and Ron Banks and Westlund, {Karin N.} and Yates, {Bill J.} and Jerald Silverman and Hansen, {Kenneth D.} and Barbara Redman",
note = "Funding Information: ABBREVIATIONS: AV, attending veterinarian; AWA, Animal Welfare Act; AWR, AWA regulation; DoD, U.S. Department of Defense; FOIA, Freedom of Information; IACUC, Institutional Animal Care and Use Committee; IO, institutional official; NIH, U.S. National Institutes of Health; NSF, U.S. National Science Foundation; OLAW, Office of Laboratory Animal Welfare; PHS, U.S. Public Health Service; PI, principal investigator; USDA, U.S. Department of Agriculture 1Correspondence: Department of Internal Medicine, Morsani College of Medicine, University of South Florida, 12901 Bruce B. Downs Blvd. MDC19 Tampa, FL 33612, USA. E-mail: bhansen@health.usf.edu Funding Information: The AWA constitutes the legal authority for assuring the welfare of animals used in research. AWRs state that the IACUC must review, and, if warranted, investigate concerns that arise from the use of animals. The IACUC{\textquoteright}s investigation of noncompliance allegations must comply with all legal requirements for such investigations on the basis of the regulations and polices below and on the institution{\textquoteright}s governance frame-work. As noted above, the PHS Policy (1) states that one function of the IACUC is to review concerns that involve the care and use of animals at the institution. OLAW provides some guidance on the evaluation of such concerns in the IACUC guidebook (10), as well as in relevant notices (e.g., NOD-OD-05-034) (11). In addition, the IACUC handbook (12) offers suggestions. The PHS policy covers extramural or intramural activities that are funded by the NIH, the U.S. Food and Drug Administration, the Center for Disease Control and Prevention, and the Department of Health and Human Services, and also covers—via a memorandum of understanding— activities that are funded by the U.S. National Science Foundation (NSF). Other agencies and institutions, such as the U.S. Department of Veterans Affairs and some U.S. Department of Defense (DoD) facilities, have individual OLAW assurances agreeing to adhere to the policy. Publisher Copyright: {\textcopyright} FASEB.",
year = "2017",
month = oct,
doi = "10.1096/fj.201601250R",
language = "English (US)",
volume = "31",
pages = "4216--4225",
journal = "FASEB Journal",
issn = "0892-6638",
publisher = "FASEB",
number = "10",
}