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Engineering allosteric regulation in protein kinases
David Pincus
, Jai P. Pandey
, Zoë A. Feder
, Pau Creixell
, Orna Resnekov
, Kimberly A Reynolds
The Green Center for Systems Biology
Green Center For Systems Biology
Biophysics
Research output
:
Contribution to journal
›
Article
›
peer-review
23
Scopus citations
Overview
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Keyphrases
Protein Kinase
100%
Allosteric Regulation
100%
Phosphoregulation
100%
Clinical Significance
33%
Active Sites
33%
Kinase Activity
33%
Regulatory Mechanism
33%
Cell Signaling
33%
Mitogen-activated Protein Kinase
33%
Cellular Response
33%
Human Disease
33%
In Cancer
33%
Phosphorylation Sites
33%
Negatively Charged
33%
Protein Activity
33%
Kinome
33%
Signaling Dynamics
33%
Regulatory Site
33%
Phosphate Group
33%
Synthetic Biology
33%
Spatially Distributed
33%
Hog1
33%
Biochemistry, Genetics and Molecular Biology
Kinase
100%
Phosphotransferase
100%
Protein Kinases
100%
Allosteric Regulation
100%
Signal Transduction
50%
Active Site
50%
Mitogen-Activated Protein Kinase
50%
Surface Property
50%
Dynamics
50%
Kinome
50%
Regulatory Site
50%