Engagement, Exploitation, and Human Intracranial Electrophysiology Research

Michelle T. Pham, Nader Pouratian, Ashley Feinsinger

Research output: Contribution to journalArticlepeer-review


Motivated by exploitation concerns, we argue for the importance of participant engagement in basic human intracranial electrophysiology research. This research takes advantage of unique neurosurgical opportunities to better understand complex systems of the human brain, but it also exposes participants to additional risks without immediate therapeutic intent. We argue that understanding participant values and incorporating their perspectives into the research process may (i) help determine whether and to what extent research practices and the resulting distributions of risks and benefits constitute exploitation and (ii) contribute to building a brain research paradigm that is genuinely responsive to participant values. More broadly, we highlight the importance of paying attention to participant interests in non-therapeutic brain research.

Original languageEnglish (US)
Article number25
Issue number3
StatePublished - Oct 2022


  • Engagement
  • Exploitation
  • Human intracranial electrophysiology research
  • Neuroethics

ASJC Scopus subject areas

  • Philosophy
  • Neurology
  • Health Policy
  • Psychiatry and Mental health


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