TY - JOUR
T1 - Emergent medical and surgical management of mediastinal infantile hemangioma with symptomatic spinal cord compression
T2 - Case report and literature review
AU - Fulkerson, Daniel H.
AU - Agim, Nnenna G.
AU - Al-Shamy, George
AU - Metry, Denise W.
AU - Izaddoost, Shayan A.
AU - Jea, Andrew
PY - 2010/12
Y1 - 2010/12
N2 - Purpose: We report an extremely rare case of a patient with a large, cervical, and upper thoracic cutaneous hemangioma associated with a separate, underlying mediastinal hemangioma extending to the epidural space causing significant spinal cord compression. Case report: A 6-week-old female presented with decreased movement of her right arm and bilateral lower extremity hyperreflexia. Her arm weakness progressed to paralysis over the course of 24 h. She underwent emergent surgical decompression and medical therapy with propranolol and systemic corticosteroids. Conclusion: While several recent reports have described dramatic responses of hemangiomas to propranolol, this is the first case in which it was used as part of a multimodal approach to symptomatic spinal cord compression. The infant improved immediately after surgery. She is neurologically intact and has radiographic regression of the hemangiomas on follow-up examination 6 months later.
AB - Purpose: We report an extremely rare case of a patient with a large, cervical, and upper thoracic cutaneous hemangioma associated with a separate, underlying mediastinal hemangioma extending to the epidural space causing significant spinal cord compression. Case report: A 6-week-old female presented with decreased movement of her right arm and bilateral lower extremity hyperreflexia. Her arm weakness progressed to paralysis over the course of 24 h. She underwent emergent surgical decompression and medical therapy with propranolol and systemic corticosteroids. Conclusion: While several recent reports have described dramatic responses of hemangiomas to propranolol, this is the first case in which it was used as part of a multimodal approach to symptomatic spinal cord compression. The infant improved immediately after surgery. She is neurologically intact and has radiographic regression of the hemangiomas on follow-up examination 6 months later.
KW - Infantile hemangioma
KW - Myelopathy
KW - Pediatric spine
KW - Propranolol
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U2 - 10.1007/s00381-010-1153-7
DO - 10.1007/s00381-010-1153-7
M3 - Article
C2 - 20405131
AN - SCOPUS:78649321265
SN - 0256-7040
VL - 26
SP - 1799
EP - 1805
JO - Child's Nervous System
JF - Child's Nervous System
IS - 12
ER -