Embryology of the umbilicus and associated newborn defects

Robert K. Minkes, Mark V. Mazziotti

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations


Congenital abdominal wall abnormalities are a common group of disorders that result from abnormal development of the abdominal wall. Ventral body wall defects range from the relatively minor umbilical and epigastric hernias to major defects such as gastroschisis and omphalocele. This chapter will focus on the embryology of the umbilicus and associated common umbilical defects and postnatal problems. The physiologic importance of the umbilicus and umbilical cord is far greater during fetal development than it is after birth. During abdominal wall development, the developing umbilicus serves a role in intestinal and urinary development and provides a life-sustaining opening that allows blood to flow between the placenta and fetus via the umbilical cord. After birth this conduit is no longer needed, and once the umbilical cord falls off, there should be no remaining connections. Nevertheless, umbilical disorders are frequently encountered.

Original languageEnglish (US)
Title of host publicationPediatric Umbilical Reconstruction
Subtitle of host publicationPrinciples and Techniques
PublisherSpringer International Publishing
Number of pages18
ISBN (Electronic)9783319438900
ISBN (Print)9783319438887
StatePublished - Aug 9 2017

ASJC Scopus subject areas

  • General Medicine


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