TY - CHAP
T1 - Embelin and its role in chronic diseases
AU - Lu, Hong
AU - Wang, Jun
AU - Wang, Youxue
AU - Qiao, Liang
AU - Zhou, Yongning
N1 - Funding Information:
This work was supported by the grant “The Model for Prevention and Control of Malignant Tumor in Area with High Incidence from Wuwei Gansu Province” (National Science and Technology Program, Grant Code: 2012GS620101 to YN Zhou).
Publisher Copyright:
© Springer International Publishing Switzerland 2016.
PY - 2016/9/1
Y1 - 2016/9/1
N2 - Embelia ribes Burm of Myrsinaceae family has been widely used as an herb in the traditional medicine of India. Embelin is an active component extracted from the fruits of Embelia ribes. It has a wide spectrum of biological activities and is not toxic at low dose. This review focuses on the physical–chemical properties and bioactivities of Embelin, as well as its effects on chronic diseases such as tumors, autoimmune inflammatory diseases, parasitic infections, microbial infections, diabetes, obesity, and cardio-cerebral vascular diseases. The underlying mechanisms of the effects are also discussed. As a multiple-targeted therapeutic agent, Embelin has the potential to be used widely for the treatment of a variety of chronic diseases, including malignant tumors.
AB - Embelia ribes Burm of Myrsinaceae family has been widely used as an herb in the traditional medicine of India. Embelin is an active component extracted from the fruits of Embelia ribes. It has a wide spectrum of biological activities and is not toxic at low dose. This review focuses on the physical–chemical properties and bioactivities of Embelin, as well as its effects on chronic diseases such as tumors, autoimmune inflammatory diseases, parasitic infections, microbial infections, diabetes, obesity, and cardio-cerebral vascular diseases. The underlying mechanisms of the effects are also discussed. As a multiple-targeted therapeutic agent, Embelin has the potential to be used widely for the treatment of a variety of chronic diseases, including malignant tumors.
KW - Anthelmintic activity
KW - Anticancer activity
KW - Antimicrobial activity
KW - Autoimmune inflammatory diseases
KW - Cardio-cerebral vascular diseases
KW - Diabetes
KW - Embelin
UR - http://www.scopus.com/inward/record.url?scp=84988930920&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84988930920&partnerID=8YFLogxK
U2 - 10.1007/978-3-319-41334-1_16
DO - 10.1007/978-3-319-41334-1_16
M3 - Chapter
C2 - 27671825
AN - SCOPUS:84988930920
T3 - Advances in Experimental Medicine and Biology
SP - 397
EP - 418
BT - Advances in Experimental Medicine and Biology
PB - Springer New York LLC
ER -