Elucidating the relationship between negative affectivity and symptoms: The role of illness-specific affective responses

Pablo A. Mora, Ethan Hahn, Howard Leventhal, Francisco Ceric

Research output: Contribution to journalArticlepeer-review

40 Scopus citations


Background: More than 20 years of research confirm a positive association of trait negative affect (NA) with reports of physical symptoms. As the mechanisms underlying the association of trait NA and symptom reporting have not been identified, the meaning of the association remains unclear. Purpose: We attempted to clarify the processes underlying this association by examining the relationship of trait NA and illness-specific worry to both vague, general symptoms and illness-specific symptoms. We tested the hypothesis that trait NA has both a "biasing" effect when ambiguous symptoms are interpreted as a sign of physical illness and an "accuracy" effect on the reports of illness-specific symptoms mediated by illness-specific worry. Method: We examined the relationship of trait and state NA to symptoms reports in both cross-sectional and longitudinal data from inner-city adults with moderate and severe asthma. Results: Whereas high levels of trait NA were associated with reports of both asthma and nonasthma symptoms, only the relationship of trait NA to symptoms specific to asthma was mediated by asthma worry. In addition, these data showed that trait NA was not associated with the misattribution of symptoms to disease. Conclusions: We concluded that NA motivates individuals, through asthma worry, to be more aware of illness-specific symptoms and correctly report and attribute these symptoms to asthma.

Original languageEnglish (US)
Pages (from-to)77-86
Number of pages10
JournalAnnals of Behavioral Medicine
Issue number1
StatePublished - 2007

ASJC Scopus subject areas

  • Psychology(all)
  • Psychiatry and Mental health


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