ELISA HIV testing and viral culture in the screening of corneal tissue for transplant from medical examiner cases

E. Heck; C. Petty; A. Palestine; M. Luckenbach; S. Z. Salahuddin; R. Nussenblatt; W. Harris; C. Baxter; James P McCulley

doi:10.1097/00003226-198906000-00001

ELISA HIV testing and viral culture in the screening of corneal tissue for transplant from medical examiner cases

E. Heck, C. Petty, A. Palestine, M. Luckenbach, S. Z. Salahuddin, R. Nussenblatt, W. Harris, C. Baxter, James P McCulley

Research output: Contribution to journal › Article › peer-review

14 Scopus citations

Abstract

The spread of AIDS and its association with a retrovirus, commonly called T-lymphotropic virus type III (HIV) has produced great concern among those involved in transplantation about the possibility for transmission of this disease through tissue and organ transplant. Isolation of the virus from conjunctiva and tears further heightened this concern for corneal transplants. This review of medical examiner (ME) cases, a population in which high numbers of transplant corneas are retrieved, has revealed positive serologic tests for HIV in serum from 5 cases in 205 screens. These represent potential donors based on other standard medical criteria available at the time of collection. This tissue was also submitted for viral culture, and virus was recovered from the corneal tissue in McCarey-Kaufman (MK) media. These findings and case reviews are discussed.

Original language	English (US)
Pages (from-to)	77-80
Number of pages	4
Journal	Cornea
Volume	8
Issue number	2
DOIs	https://doi.org/10.1097/00003226-198906000-00001
State	Published - 1989

ASJC Scopus subject areas

Ophthalmology

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10.1097/00003226-198906000-00001

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title = "ELISA HIV testing and viral culture in the screening of corneal tissue for transplant from medical examiner cases",

abstract = "The spread of AIDS and its association with a retrovirus, commonly called T-lymphotropic virus type III (HIV) has produced great concern among those involved in transplantation about the possibility for transmission of this disease through tissue and organ transplant. Isolation of the virus from conjunctiva and tears further heightened this concern for corneal transplants. This review of medical examiner (ME) cases, a population in which high numbers of transplant corneas are retrieved, has revealed positive serologic tests for HIV in serum from 5 cases in 205 screens. These represent potential donors based on other standard medical criteria available at the time of collection. This tissue was also submitted for viral culture, and virus was recovered from the corneal tissue in McCarey-Kaufman (MK) media. These findings and case reviews are discussed.",

author = "E. Heck and C. Petty and A. Palestine and M. Luckenbach and Salahuddin, {S. Z.} and R. Nussenblatt and W. Harris and C. Baxter and McCulley, {James P}",

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T1 - ELISA HIV testing and viral culture in the screening of corneal tissue for transplant from medical examiner cases

AU - Heck, E.

AU - Petty, C.

AU - Palestine, A.

AU - Luckenbach, M.

AU - Salahuddin, S. Z.

AU - Nussenblatt, R.

AU - Harris, W.

AU - Baxter, C.

AU - McCulley, James P

PY - 1989

Y1 - 1989

N2 - The spread of AIDS and its association with a retrovirus, commonly called T-lymphotropic virus type III (HIV) has produced great concern among those involved in transplantation about the possibility for transmission of this disease through tissue and organ transplant. Isolation of the virus from conjunctiva and tears further heightened this concern for corneal transplants. This review of medical examiner (ME) cases, a population in which high numbers of transplant corneas are retrieved, has revealed positive serologic tests for HIV in serum from 5 cases in 205 screens. These represent potential donors based on other standard medical criteria available at the time of collection. This tissue was also submitted for viral culture, and virus was recovered from the corneal tissue in McCarey-Kaufman (MK) media. These findings and case reviews are discussed.

AB - The spread of AIDS and its association with a retrovirus, commonly called T-lymphotropic virus type III (HIV) has produced great concern among those involved in transplantation about the possibility for transmission of this disease through tissue and organ transplant. Isolation of the virus from conjunctiva and tears further heightened this concern for corneal transplants. This review of medical examiner (ME) cases, a population in which high numbers of transplant corneas are retrieved, has revealed positive serologic tests for HIV in serum from 5 cases in 205 screens. These represent potential donors based on other standard medical criteria available at the time of collection. This tissue was also submitted for viral culture, and virus was recovered from the corneal tissue in McCarey-Kaufman (MK) media. These findings and case reviews are discussed.

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ELISA HIV testing and viral culture in the screening of corneal tissue for transplant from medical examiner cases

Abstract

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