@article{c3dbb76643c14b8b97a5abdb21b72bbb,
title = "EglN2 positively regulates mitochondrial function in breast cancer",
abstract = "Oxygen sensing is associated with mitochondrial function. EglN2, which contributes to breast tumorigenesis as a prolyl hydroxylase, has recently been identified as a transcription co-activator through interaction with NRF1 and PGC1α to regulate mitochondrial function under conditions of normoxia and hypoxia. FDXR is the important downstream target gene that mediates this regulation.",
keywords = "Breast cancer, EglN2, FDXR, hypoxia, mitochondria",
author = "Jing Zhang and Xingnan Zheng and Qing Zhang",
note = "Funding Information: This work was partially supported by a grant from the US National Institute of Health/National Cancer Institute (R00CA160351) to QZ, the University Cancer Research Fund from University of North Carolina at Chapel Hill to QZ, a Kimmel Scholar Award from Sidney Kimmel Foundation to QZ, The V Foundation Scholar Award from the V Foundation for Cancer Research to QZ, and a Susan G. Komen Career Catalyst Award to QZ. Publisher Copyright: {\textcopyright} 2016, {\textcopyright} 2016 The Author(s). Published with license by Taylor & Francis Group, LLC. {\textcopyright} 2016, {\textcopyright} Jing Zhang, Xingnan Zheng, and Qing Zhang.",
year = "2016",
month = mar,
day = "3",
doi = "10.1080/23723556.2015.1120845",
language = "English (US)",
volume = "3",
journal = "Molecular and Cellular Oncology",
issn = "2372-3556",
publisher = "Taylor and Francis Ltd.",
number = "2",
}