Effects of misclassifications on statistical inferences in epidemiology

Dana Quade, Peter A. Lachenbruch, Fredrick S. Whaley, Donna K. Mcclish, Robert W. Haley

Research output: Contribution to journalArticlepeer-review

81 Scopus citations


Misclasslfication errors caused by Imperfect sensttlvlty (U) and speclflclty (V) can affect statistical Inferences in epidemiology. Such errors can lead to blases and Increased standard errors In estimates of rates. Furthermore, low U and V can have a catastrophic effect on the power of a test to detect a change In rate, and, if U and V change even slightly as the rate changes, the effect on power may be dramatlc.

Original languageEnglish (US)
Pages (from-to)503-515
Number of pages13
JournalAmerican Journal of Epidemiology
Issue number5
StatePublished - May 1980


  • Biometry
  • Epldemlologic methods
  • Statlstlcs

ASJC Scopus subject areas

  • Epidemiology


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