TY - JOUR
T1 - Effect of propranolol versus no propranolol on total mortality plus nonfatal myocardial infarction in older patients with prior myocardial infarction, congestive heart failure, and left ventricular ejection fraction ≤40% treated with diuretics plus angiotensin-converting enzyme inhibitors
AU - Aronow, Wilbert S.
AU - Ahn, Chul
AU - Kronzon, Itzhak
PY - 1997/7/15
Y1 - 1997/7/15
N2 - At 32-month follow-up of older patients with prior myocardial infarction, congestive heart failure, and a left ventricular ejection fraction ≤40% treated with diuretics plus angiotensin-converting enzyme inhibitors, and also with digoxin if atrial fibrillation was present, propranolol caused a 35% significant reduction in total mortality and a 37% significant decrease in total mortality plus nonfatal myocardial infarction compared with no propranolol. At 1-year follow-up, propranolol caused a significantly greater increase in left ventricular ejection fraction (6%) and a significantly greater reduction in left ventricular mass (34 g) than did no propranolol (2% and 20 g, respectively).
AB - At 32-month follow-up of older patients with prior myocardial infarction, congestive heart failure, and a left ventricular ejection fraction ≤40% treated with diuretics plus angiotensin-converting enzyme inhibitors, and also with digoxin if atrial fibrillation was present, propranolol caused a 35% significant reduction in total mortality and a 37% significant decrease in total mortality plus nonfatal myocardial infarction compared with no propranolol. At 1-year follow-up, propranolol caused a significantly greater increase in left ventricular ejection fraction (6%) and a significantly greater reduction in left ventricular mass (34 g) than did no propranolol (2% and 20 g, respectively).
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U2 - 10.1016/S0002-9149(97)00320-2
DO - 10.1016/S0002-9149(97)00320-2
M3 - Article
C2 - 9230162
AN - SCOPUS:0030853984
SN - 0002-9149
VL - 80
SP - 207
EP - 209
JO - American Journal of Cardiology
JF - American Journal of Cardiology
IS - 2
ER -