Effect of linolenic acid and its hydroxamic derivative on 5-lipoxygenase

L. B. Bondarenko, S. A. Ohiy, I. A. Butovich

Research output: Contribution to journalArticlepeer-review


In experiments with micellar in vitro system comparative study oflinoleic and linolenic acids and also their hydroxamic derivatives effects on 5-lipoxygenase from potato tubers was carried out. It was shown that less effectivness of linolenic acid as substrate of 5-lipoxygenase (in comparison with linoleic acid) correlated with less inhibitory effect oflinolenate hydroxamic acid (in comparison with linoleate hydroxamic acid) on this enzyme. Effects of investigated compounds depended on pH and substrate concentrations.

Original languageEnglish (US)
Pages (from-to)34-37
Number of pages4
JournalBiopolymers and Cell
Issue number2
StatePublished - 1996

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)


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