Abstract
The effect of hepatic irradiation on adriamycin toxicity and pharmacokinetics was studied in 10 children who received adriamycin with concurrent abdominal irradiation for Wilms' tumor. Hepatic irradiation to 2400-2700 rad at 100-150 rad per fraction did not alter the clinical toxicity or plasma pharmacokinetics of adriamycin.
Original language | English (US) |
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Pages (from-to) | 953-956 |
Number of pages | 4 |
Journal | International journal of radiation oncology, biology, physics |
Volume | 7 |
Issue number | 7 |
DOIs | |
State | Published - Jul 1981 |
Keywords
- Adriamycin
- Hepatic irradiation
- Pharmacokinetics
- Toxicity
- Wilms' tumor
ASJC Scopus subject areas
- Radiation
- Oncology
- Radiology Nuclear Medicine and imaging
- Cancer Research