Early Detection and Staging of Adenocarcinoma of the Pancreas

Sam Pappas, Michael P. Federle, Anna E. Lokshin, Herbert J. Zeh

Research output: Contribution to journalReview articlepeer-review

9 Scopus citations


Early diagnosis is likely to improve the outcome and survival in patients who have pancreatic cancer. The sensitivity and specificity of current screening methods, however, limit their applicability to individuals at high risk for developing pancreatic cancer. Further development of serum markers may lead to improved diagnostic accuracy and allow screening to be implemented more broadly. Proteomic profiling and evaluation of panels of markers hold particular promise for the future. This article provides a review of current methods and results for the early detection and staging of pancreatic cancer, and discusses some potential areas for future development.

Original languageEnglish (US)
Pages (from-to)413-429
Number of pages17
JournalGastroenterology Clinics of North America
Issue number2
StatePublished - Jun 2007
Externally publishedYes

ASJC Scopus subject areas

  • Gastroenterology


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