E-cigarettes and asthma in adolescents

Research output: Contribution to journalReview articlepeer-review


Purpose of reviewE-cigarettes have been long purported to be a mechanism of harm reduction in current smokers. However, market expansion to adolescents has been aggressive, despite government interventions. Research examining the adverse effects of e-cigarettes in teens with asthma has been limited. We discuss the most recent data on the pulmonary manifestations of e-cigarettes use and exposure in adolescents with asthma.Recent findingsAdolescents with asthma are more likely to be e-cigarette users than those without asthma and more likely to have asthma exacerbations. Increased pulmonary inflammatory cytokines have been seen in e-cigarette users and mouse models. Yet, providers are not confident in e-cigarette screening and counselling despite acknowledging adolescents are using e-cigarettes regularly.SummarySince the introduction of e-cigarettes into the United States market in 2007, adolescents use of these products has risen, even after a brief decline during the height of the COVID-19 pandemic. This review will describe the most recent studies on e-cigarette use trends, cytotoxicity of e-cigarette aerosol and associations with the diagnosis and symptoms of asthma. Knowledge gaps, advocacy efforts, evidence on e-cigarette cessation will be highlighted.

Original languageEnglish (US)
Pages (from-to)137-143
Number of pages7
JournalCurrent Opinion in Allergy and Clinical Immunology
Issue number2
StatePublished - Apr 1 2023


  • adolescents
  • asthma
  • E-cigarette
  • lung disease
  • marijuana
  • tobacco
  • vaping

ASJC Scopus subject areas

  • Medicine(all)


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