Abstract
Although acute liver failure caused by drug-induced liver injury comprises a small fraction of overall drug-induced liver injury, these patients require high resource use and have relatively poor outcomes. Drug-induced liver injury caused by idiosyncrasy more often leads to death or transplantation than does acetaminophen acute liver failure, but the number of patients in each category receiving a graft is roughly the same. Efforts in the future to improve outcomes should focus on more effective treatments and better methods to identify those that might experience poor outcomes.
Original language | English (US) |
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Pages (from-to) | 575-586 |
Number of pages | 12 |
Journal | Clinics in Liver Disease |
Volume | 17 |
Issue number | 4 |
DOIs | |
State | Published - Nov 2013 |
Keywords
- Coagulopathy
- Encephalopathy
- Hepatocyte injury
- Liver transplantation
ASJC Scopus subject areas
- Hepatology