TY - JOUR
T1 - Dopaminergic rules of engagement for memory in Drosophila
AU - Kaun, Karla R.
AU - Rothenfluh, Adrian
N1 - Publisher Copyright:
© 2017 Elsevier Ltd
PY - 2017/4/1
Y1 - 2017/4/1
N2 - Dopamine is associated with a variety of conserved responses across species including locomotion, sleep, food consumption, aggression, courtship, addiction and several forms of appetitive and aversive memory. Historically, dopamine has been most prominently associated with dynamics underlying reward, punishment, or salience. Recent emerging evidence from Drosophila supports a role in all of these functions, as well as additional roles in the interplay between external sensation and internal states and forgetting of the very memories dopamine helped encode. We discuss how cell-specific resolution and manipulation are elucidating the rules of dopamine's involvement in encoding valence and memory.
AB - Dopamine is associated with a variety of conserved responses across species including locomotion, sleep, food consumption, aggression, courtship, addiction and several forms of appetitive and aversive memory. Historically, dopamine has been most prominently associated with dynamics underlying reward, punishment, or salience. Recent emerging evidence from Drosophila supports a role in all of these functions, as well as additional roles in the interplay between external sensation and internal states and forgetting of the very memories dopamine helped encode. We discuss how cell-specific resolution and manipulation are elucidating the rules of dopamine's involvement in encoding valence and memory.
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U2 - 10.1016/j.conb.2016.12.011
DO - 10.1016/j.conb.2016.12.011
M3 - Review article
C2 - 28088703
AN - SCOPUS:85009062742
SN - 0959-4388
VL - 43
SP - 56
EP - 62
JO - Current Opinion in Neurobiology
JF - Current Opinion in Neurobiology
ER -