Abstract
To what extent are the pathways that regulate self-renewal conserved between stem cells at different stages of development and in different tissues? Some pathways play a strikingly conserved role in regulating the self-renewal of diverse stem cells, whereas other pathways are specific to stem cells in certain tissues or at certain stages of development. Recent studies have highlighted differences between the self-renewal of embryonic, fetal and adult stem cells. By understanding these similarities and differences we may come to a molecular understanding of how stem cells replicate themselves and why aspects of this process differ between stem cells.
Original language | English (US) |
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Pages (from-to) | 700-707 |
Number of pages | 8 |
Journal | Current Opinion in Cell Biology |
Volume | 16 |
Issue number | 6 |
DOIs | |
State | Published - Dec 2004 |
ASJC Scopus subject areas
- Cell Biology