Direct transition metal-catalyzed functionalization of heteroaromatic compounds

Ilya V. Seregin, Vladimir Gevorgyan

Research output: Contribution to journalArticlepeer-review

1521 Scopus citations


During the last two decades there has been considerable growth in the development of catalytic reactions capable of activating unreactive C–H bonds. These methods allow for the synthesis of complex molecules from easily available and cheaper precursors in a fewer number of steps. Naturally, the development of C–H activation methods for direct functionalization of heterocyclic molecules, invaluable building blocks for pharmaceutical and synthetic chemistry and material science, has received substantial attention as well. This critical review summarizes the progress made in this field until November 2006 (117 references).

Original languageEnglish (US)
Pages (from-to)1173-1193
Number of pages21
JournalChemical Society Reviews
Issue number7
StatePublished - Jun 18 2007
Externally publishedYes

ASJC Scopus subject areas

  • General Chemistry


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