Direct transfer of adult hookworms (Ancylostoma duodenale) from dog to child for therapeutic purposes

J. N. Walterspiel, G. A. Schad, G. R. Buchanan

Research output: Contribution to journalArticlepeer-review


To induce chronic and continuous intestinal blood loss as therapy for congenital polycythemia in a 3 year old child, adult Ancylostoma duodenale were transferred directly from a dog to the patient via a nasoduodenal tube. By transferring adult worms, larval migration via the skin, blood and lungs - with possible attendant undesired side effects - was avoided. Furthermore, by eliminating larval migration with associated intimate tissue contact, immunogenicity was presumably reduced, and a known number of adult worms could be delivered directly to the final predilection site, the small intestine. An eosinophilic reaction of up to 23,000 cells/mm3 was observed, which may have adversely affected attempted superinfection. The relatively small numbers of parasites given on three separate occasions did not result in blood loss to a degree sufficient to eliminate the need for other forms of therapy.

Original languageEnglish (US)
Pages (from-to)217-219
Number of pages3
JournalJournal of Parasitology
Issue number2
StatePublished - Jan 1 1984

ASJC Scopus subject areas

  • Parasitology
  • Ecology, Evolution, Behavior and Systematics


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