Dimeric pyrrole–imidazole alkaloids: Synthetic approaches and biosynthetic hypotheses

Xiao Wang; Zhiqiang Ma; Xiaolei Wang; Saptarshi De; Yuyong Ma; Chuo Chen

doi:10.1039/c4cc02290d

Dimeric pyrrole–imidazole alkaloids: Synthetic approaches and biosynthetic hypotheses

Xiao Wang, Zhiqiang Ma, Xiaolei Wang, Saptarshi De, Yuyong Ma, Chuo Chen

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53 Scopus citations

Abstract

The pyrrole–imidazole alkaloids are a group of structurally unique and biologically interesting marine sponge metabolites. Among them, the cyclic dimers have caught synthetic chemists' attention particularly. Numerous synthetic strategies have been developed and various biosynthetic hypotheses have been proposed for these fascinating natural products. We discuss herein the synthetic approaches and the biosynthetic insights obtained from these studies.

Original language	English (US)
Pages (from-to)	8628-8639
Number of pages	12
Journal	Chemical Communications
Volume	50
Issue number	63
DOIs	https://doi.org/10.1039/c4cc02290d
State	Published - Jul 10 2014

ASJC Scopus subject areas

Catalysis
Electronic, Optical and Magnetic Materials
Ceramics and Composites
Chemistry(all)
Surfaces, Coatings and Films
Metals and Alloys
Materials Chemistry

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abstract = "The pyrrole–imidazole alkaloids are a group of structurally unique and biologically interesting marine sponge metabolites. Among them, the cyclic dimers have caught synthetic chemists' attention particularly. Numerous synthetic strategies have been developed and various biosynthetic hypotheses have been proposed for these fascinating natural products. We discuss herein the synthetic approaches and the biosynthetic insights obtained from these studies.",

author = "Xiao Wang and Zhiqiang Ma and Xiaolei Wang and Saptarshi De and Yuyong Ma and Chuo Chen",

year = "2014",

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T2 - Synthetic approaches and biosynthetic hypotheses

AU - Wang, Xiao

AU - Ma, Zhiqiang

AU - Wang, Xiaolei

AU - De, Saptarshi

AU - Ma, Yuyong

AU - Chen, Chuo

PY - 2014/7/10

Y1 - 2014/7/10

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AB - The pyrrole–imidazole alkaloids are a group of structurally unique and biologically interesting marine sponge metabolites. Among them, the cyclic dimers have caught synthetic chemists' attention particularly. Numerous synthetic strategies have been developed and various biosynthetic hypotheses have been proposed for these fascinating natural products. We discuss herein the synthetic approaches and the biosynthetic insights obtained from these studies.

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Dimeric pyrrole–imidazole alkaloids: Synthetic approaches and biosynthetic hypotheses

Abstract

ASJC Scopus subject areas

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