Diastolic Stress Testing Along the Heart Failure Continuum

T. Jake Samuel, Rhys Beaudry, Satyam Sarma, Vlad Zaha, Mark J. Haykowsky, Michael D. Nelson

Research output: Contribution to journalReview articlepeer-review

2 Scopus citations


Purpose of Review: This review summarizes recent developments highlighting the clinical utility of diastolic stress testing along the heart failure continuum. Recent Findings: Invasive hemodynamic assessment of cardiac filling pressures during physiological stress is the gold-standard technique for unmasking diastolic dysfunction. Non-invasive surrogate techniques, such as Doppler ultrasound, have shown excellent agreement with invasive approaches and are now recommended by the American Society of Echocardiography and the European Association of Cardiovascular Imaging. While cycle exercise is often advocated, recent evidence supports the use of isometric handgrip as a viable alternative stressor. Summary: Diastolic stress testing is a powerful tool to enhance detection of diastolic dysfunction, is able to differentiate between cardiac and non-cardiac pathology, and should be incorporated into routine clinical assessment.

Original languageEnglish (US)
Pages (from-to)332-339
Number of pages8
JournalCurrent heart failure reports
Issue number6
StatePublished - Dec 1 2018


  • Cycle exercise
  • Diastolic stress testing
  • Exertional dyspnea
  • Heart failure
  • Isometric handgrip

ASJC Scopus subject areas

  • Emergency Medicine
  • Cardiology and Cardiovascular Medicine
  • Physiology (medical)


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