@article{af771b23c2d6449c83988eec766cc0c2,
title = "Diamond-Blackfan syndrome in adult patients",
abstract = "Two adults with pure red cell aplasia are described. No extrinsic etiologic mechanisms were identified. Evidence of anemia was long-standing and varied in severity. Musculoskeletal abnormalities (webbed neck, Sprengel's and Klippel-Feil deformities, and hand abnormalities) were similar to those seen in the congenital form of red cell aplasia (Diamond-Blackfan syndrome). As in the congenital variety, adrenal cortical steroids resulted in hematologic repair. These observations suggest that congenital (Diamond-Blackfan) pure red cell aplasia may be first recognized in adulthood and that steroids provide a potential therapeutic modality.",
author = "Balaban, {Edward P.} and Buchanan, {George R.} and Mateel Graham and Frenkel, {Eugene P.}",
note = "Funding Information: From the Departments of internal Medicine and Pediatrics, University of Texas Health Science Center, Veterans Administration Hospital, Dallas, Texas. This wcrk was supported by United States Public He&h Service, Natknai instiMes of He&h Grant CA-18132, Bethesda, Maryland, the Meadows Foundation, Dallas, Texas, and the South-western Medical Foundation-Kinsier Williamson Brown Fund, Dallas, Texas. Dr. Baiabsn is a Clinical Fellow of the American Cancer Society. Requests for reprints shoukl be addressed to Dr. Edward P. B&ban, Department of internal Medicine, University of Texas Health Science Center, 5323 Hany Hines Boulevard, Daiks, Texas 75235. Manuscript accepted May 15, 1984 Two adults with pure red cell aplasla are described. No extrinsic etiologic mechanisms were identified. Evidence of anemia was long-standing and varied in severity. Musculoskeletal abnormalities (webbed neck, Sprengel{\textquoteright}s and Klippel-Fell deformities, and hand abnormalities) were similar to those seen in the congenital form of red cell aplasia (Diamond-Blackfan syndrome). As in the congenital variety, adrenal cortical steroids resulted in hematologic repair. These observations suggest that congenital (Diamond-Blackfan) pure red cell aplasia may be first recognized in adulthood and that steroids provide a potential therapeutic modality.",
year = "1985",
month = mar,
doi = "10.1016/0002-9343(85)90352-3",
language = "English (US)",
volume = "78",
pages = "533--538",
journal = "The American Journal of Medicine",
issn = "0002-9343",
publisher = "Elsevier Inc.",
number = "3",
}