Abstract
The detection of blood stream infections is one of the most important functions of the clinical microbiology laboratory. Sepsis is a clinical emergency, and mortality increases if commencement of appropriate antimicrobial therapy is delayed. Automated blood culture systems are the most sensitive approach for detection of the causative agent of sepsis. Several laboratory methods have been developed to expedite identification of organisms directly from positive blood culture broth. The principle and analytical performance characteristics of these methods are described in this review.
Original language | English (US) |
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Pages (from-to) | 651-684 |
Number of pages | 34 |
Journal | Clinics in laboratory medicine |
Volume | 33 |
Issue number | 3 |
DOIs | |
State | Published - Sep 2013 |
Keywords
- Bacteremia
- Blood culture
- MRSA
- Molecular diagnostics
- Rapid pathogen detection
- Staphylococcus aureus
ASJC Scopus subject areas
- Clinical Biochemistry
- Biochemistry, medical