TY - JOUR
T1 - Diagnosing the GOSE
T2 - Structural and Psychometric Properties Using Item Response Theory, a TRACK-TBI Pilot Study
AU - TRACK-TBI Investigators
AU - Ranson, Jana
AU - Magnus, Brooke E.
AU - Temkin, Nancy
AU - Dikmen, Sureyya
AU - Giacino, Joseph T.
AU - Okonkwo, David O.
AU - Valadka, Alex B.
AU - Manley, Geoffrey T.
AU - Nelson, Lindsay D.
N1 - Funding Information:
This work was supported by the National Institutes of Health (grant nos. RC2 NS0694909 [to G.T.M.], RC2 NS069409-02S1 [to G.T.M.], and R03 NS100691-01 [to L.D.N.]) and the Department of Defense (USAMRAA W81XWH-13-1-0441; to G.T.M.). Registry: ClinicalTrials.gov Identifier NCT01565551. Editorial support was provided by Amy J. Markowitz, JD.
Funding Information:
Dr. Temkin reports grants from the Department of Defense, NIH, NIDILRR, and CDC during the conduct of the study. Dr. Dikmen reports grants from NIH and NIDILRR during the conduct of the study. Dr. Giacino reports grants from the Department of Defense, NIH, NIDILRR, James S. McDonnell Foundation, and other support from the Barbara Epstein Foundation during the conduct of the study. Dr. Okonkwo reports grants from NIH and the Department of Defense during the conduct of the study. Dr. Manley reports grants from the Department of Defense, NIH, and other support from One Mind, Palantir, and Johnson & Johnson Family of Companies/DePuySynthes/Codman Neuro during the conduct of the study. Dr. Nelson reports grants from NIH and the Medical College of Wisconsin’s Center for Patient Care and Outcomes Research, Clinical and Translational Science Institute, and Advancing a Healthier Wisconsin Endowment during the conduct of the study.
Publisher Copyright:
© Copyright 2019, Mary Ann Liebert, Inc., publishers 2019.
PY - 2019/9
Y1 - 2019/9
N2 - The Glasgow Outcome Scale-Extended (GOSE) was designed to assess global outcome after traumatic brain injury (TBI). Since its introduction, several empirically founded criticisms of the GOSE have been raised, including poor reliability; an insensitivity to small, but potentially meaningful, changes; a tendency to produce ceiling effects; inconsistent associations with neurocognitive, psychological, and quality-of-life measures; and an inability to assess the multi-dimensional nature of TBI outcome. The current project took a diagnostic approach to identifying the underlying causes of reported limitations by exploring the internal construct validity of the GOSE at 3 and 6 months post-injury using item response theory (IRT) techniques. Data were from the TRACK-TBI Pilot Study, a large (N = 586), prospective, multi-site project that included TBI cases of all injury severity levels. To assess the level of latent functional "impairment" captured by GOSE items independent of the assigned outcome category or GOSE total score, items were modified so that higher scores reflected greater impairment. Results showed that although the GOSE's items capture varying levels of impairment across a broad disability spectrum at 3 and 6 months, there was also evidence at each time point of item redundancy (multiple items capturing similar levels of impairment), item deficiency (lack of items capturing lower levels of impairment), and item inefficiency (items only capturing minimal impairment information). The findings illustrate the value of IRT to illuminate strengths and weaknesses of clinical outcome assessment measures and provide a framework for future measure refinement.
AB - The Glasgow Outcome Scale-Extended (GOSE) was designed to assess global outcome after traumatic brain injury (TBI). Since its introduction, several empirically founded criticisms of the GOSE have been raised, including poor reliability; an insensitivity to small, but potentially meaningful, changes; a tendency to produce ceiling effects; inconsistent associations with neurocognitive, psychological, and quality-of-life measures; and an inability to assess the multi-dimensional nature of TBI outcome. The current project took a diagnostic approach to identifying the underlying causes of reported limitations by exploring the internal construct validity of the GOSE at 3 and 6 months post-injury using item response theory (IRT) techniques. Data were from the TRACK-TBI Pilot Study, a large (N = 586), prospective, multi-site project that included TBI cases of all injury severity levels. To assess the level of latent functional "impairment" captured by GOSE items independent of the assigned outcome category or GOSE total score, items were modified so that higher scores reflected greater impairment. Results showed that although the GOSE's items capture varying levels of impairment across a broad disability spectrum at 3 and 6 months, there was also evidence at each time point of item redundancy (multiple items capturing similar levels of impairment), item deficiency (lack of items capturing lower levels of impairment), and item inefficiency (items only capturing minimal impairment information). The findings illustrate the value of IRT to illuminate strengths and weaknesses of clinical outcome assessment measures and provide a framework for future measure refinement.
KW - Glasgow Outcome Scale-Extended
KW - item response theory
KW - outcome assessment
KW - psychometrics
KW - traumatic brain injury
UR - http://www.scopus.com/inward/record.url?scp=85071787074&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85071787074&partnerID=8YFLogxK
U2 - 10.1089/neu.2018.5998
DO - 10.1089/neu.2018.5998
M3 - Article
C2 - 30907261
AN - SCOPUS:85071787074
SN - 0897-7151
VL - 36
SP - 2493
EP - 2505
JO - Central Nervous System Trauma
JF - Central Nervous System Trauma
IS - 17
ER -