Diabetic foot disease in people with advanced nephropathy and those on renal dialysis

Agbor Ndip, Lawrence A. Lavery, Andrew J M Boulton

Research output: Contribution to journalReview articlepeer-review

67 Scopus citations


Among the spectrum of risk for diabetic foot disease conferred by chronic kidney disease (CKD), endstage renal disease (ESRD) has emerged as a novel independent risk factor. Apart from the classical triad of neuropathy, infection, and peripheral arterial disease that operate in these individuals, the risk is further compounded by inadequate foot self-care by patients and by dialysis centers not providing onsite foot care, as medical priorities are diverted to the dialysis itself. Consequently, the burden of diabetic foot disease has increased in the CKD and ESRD population as exemplified by high ulceration, amputation, and foot-related mortality rates. Current guidelines on foot care in diabetes should recognize advanced CKD and ESRD/dialysis as a separate risk factor for foot disease to alert professionals and highlight the opportunity for prevention. Recent studies have demonstrated improved foot outcomes when chiropody programs are instituted within dialysis units.

Original languageEnglish (US)
Pages (from-to)283-290
Number of pages8
JournalCurrent diabetes reports
Issue number4
StatePublished - Aug 2010


  • Advanced nephropathy
  • Diabetic foot disease
  • Dialysis
  • High risk

ASJC Scopus subject areas

  • Internal Medicine
  • Endocrinology, Diabetes and Metabolism


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