Dexamethasone and acute mountain sickness

John Luce, A. Bruce Montgomery, John Mills, R. T. Ross, Eyal Shahar, Benjamin D. Levine, Kazuhiko Yoshimura, Toshio Kobayashi, Masao Fukushima, Toshishige Shibamoto, Gou Ueda

Research output: Contribution to journalLetterpeer-review


To the Editor: The paper by Levine et al. (Dec. 21 issue)1 demonstrating the efficacy of dexamethasone for the treatment of experimentally induced acute mountain sickness failed to note that we documented the value of dexamethasone for acute mountain sickness three years ago, at the annual meeting of the American Thoracic Society,2 and later elsewhere.3 Our study showed that mild-to-moderate mountain sickness resulting from alpine skiing could be prevented by short-term prophylactic administration of dexamethasone in the same doses used by Levine et al. In our study, involving more than 100 patients, no evidence of serious adverse events was noted.

Original languageEnglish (US)
Pages (from-to)1395-1396
Number of pages2
JournalNew England Journal of Medicine
Issue number19
StatePublished - May 10 1990

ASJC Scopus subject areas

  • Medicine(all)


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