Development of intrinsically photoluminescent and photostable polylactones

Zhiwei Xie; Yi Zhang; Li Liu; Hong Weng; Ralph P. Mason; Liping Tang; Kytai T. Nguyen; Jer Tsong Hsieh; Jian Yang

doi:10.1002/adma.201306070

Development of intrinsically photoluminescent and photostable polylactones

Zhiwei Xie, Yi Zhang, Li Liu, Hong Weng, Ralph P. Mason, Liping Tang, Kytai T. Nguyen, Jer Tsong Hsieh, Jian Yang

Research output: Contribution to journal › Article › peer-review

57 Scopus citations

Abstract

A method of introducing intrinsically photo luminescent properties to biodegradable polymer is introduced, exemplified by the synthesis of intrinsically photoluminescent polylactones that enable non-invasive monitoring and tracking of material degradation in vivo in realtime, as well as the formation of theranostic nanoparticles for cancer imaging and drug delivery.

Original language	English (US)
Pages (from-to)	4491-4496
Number of pages	6
Journal	Advanced Materials
Volume	26
Issue number	26
DOIs	https://doi.org/10.1002/adma.201306070
State	Published - Jul 9 2014

Keywords

biodegradable polymers
fluorescence imaging
in vivo degradation
theranostic drug delivery
tissue engineering

ASJC Scopus subject areas

General Materials Science
Mechanics of Materials
Mechanical Engineering

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10.1002/adma.201306070

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abstract = "A method of introducing intrinsically photo luminescent properties to biodegradable polymer is introduced, exemplified by the synthesis of intrinsically photoluminescent polylactones that enable non-invasive monitoring and tracking of material degradation in vivo in realtime, as well as the formation of theranostic nanoparticles for cancer imaging and drug delivery.",

keywords = "biodegradable polymers, fluorescence imaging, in vivo degradation, theranostic drug delivery, tissue engineering",

author = "Zhiwei Xie and Yi Zhang and Li Liu and Hong Weng and Mason, {Ralph P.} and Liping Tang and Nguyen, {Kytai T.} and Hsieh, {Jer Tsong} and Jian Yang",

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doi = "10.1002/adma.201306070",

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AU - Xie, Zhiwei

AU - Zhang, Yi

AU - Liu, Li

AU - Weng, Hong

AU - Mason, Ralph P.

AU - Tang, Liping

AU - Nguyen, Kytai T.

AU - Hsieh, Jer Tsong

AU - Yang, Jian

PY - 2014/7/9

Y1 - 2014/7/9

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AB - A method of introducing intrinsically photo luminescent properties to biodegradable polymer is introduced, exemplified by the synthesis of intrinsically photoluminescent polylactones that enable non-invasive monitoring and tracking of material degradation in vivo in realtime, as well as the formation of theranostic nanoparticles for cancer imaging and drug delivery.

KW - biodegradable polymers

KW - fluorescence imaging

KW - in vivo degradation

KW - theranostic drug delivery

KW - tissue engineering

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Development of intrinsically photoluminescent and photostable polylactones

Abstract

Keywords

ASJC Scopus subject areas

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