Developing novel treatments for mood disorders: Accelerating discovery

Carol A. Tamminga; Charles B. Nemeroff; Randy D. Blakely; Linda Brady; Cameron S. Carter; Kenneth L. Davis; Raymond Dingledine; Jack M. Gorman; Dimitri E. Grigoriadis; David C. Henderson; Robert B. Innis; John Killen; Thomas P. Laughren; William M. McDonald; Greer M. Murphy; Steven M. Paul; Matthew V. Rudorfer; Edward Sausville; Alan F. Schatzberg; Edward M. Scolnick; Trisha Suppes

doi:10.1016/S0006-3223(02)01470-1

Developing novel treatments for mood disorders: Accelerating discovery

Carol A. Tamminga, Charles B. Nemeroff, Randy D. Blakely, Linda Brady, Cameron S. Carter, Kenneth L. Davis, Raymond Dingledine, Jack M. Gorman, Dimitri E. Grigoriadis, David C. Henderson, Robert B. Innis, John Killen, Thomas P. Laughren, William M. McDonald, Greer M. Murphy, Steven M. Paul, Matthew V. Rudorfer, Edward Sausville, Alan F. Schatzberg, Edward M. ScolnickTrisha Suppes

Research output: Contribution to journal › Review article › peer-review

73 Scopus citations

Abstract

This review was generated from discussions by the Pharmacologic and Somatic Treatments Section of the National Institute of Mental Health Strategic Plan for Mood Disorders Committee on advancing novel pharmacologic and somatic treatments for mood disorders. The opening section of the article summarizes in broad strokes, current pharmacologic treatments, and new directions in the field. Thereafter the topics focus on specific research initiatives that could advance the current therapeutics for mood disorders including new basic and clinical research in vivo human imaging procedures, somatic therapeutics, and the vast new area of pharmacogenetics. New scientific and technical opportunities exist today based on advances in basic neuroscience, opportunities in clinical testing, industry interest in advancing central nervous system therapeutics, and on active consumer advocacy groups. The question of how to bring all of these positive forces together to accelerate discovery in mood disorder therapeutics is the topic of this article.

Original language	English (US)
Pages (from-to)	589-609
Number of pages	21
Journal	Biological Psychiatry
Volume	52
Issue number	6
DOIs	https://doi.org/10.1016/S0006-3223(02)01470-1
State	Published - Sep 15 2002

Keywords

Depression bipolar disorder research resources
Government/industry collaboration

ASJC Scopus subject areas

Biological Psychiatry

Access to Document

10.1016/S0006-3223(02)01470-1

Cite this

Tamminga, C. A., Nemeroff, C. B., Blakely, R. D., Brady, L., Carter, C. S., Davis, K. L., Dingledine, R., Gorman, J. M., Grigoriadis, D. E., Henderson, D. C., Innis, R. B., Killen, J., Laughren, T. P., McDonald, W. M., Murphy, G. M., Paul, S. M., Rudorfer, M. V., Sausville, E., Schatzberg, A. F., ... Suppes, T. (2002). Developing novel treatments for mood disorders: Accelerating discovery. Biological Psychiatry, 52(6), 589-609. https://doi.org/10.1016/S0006-3223(02)01470-1

Tamminga, CA, Nemeroff, CB, Blakely, RD, Brady, L, Carter, CS, Davis, KL, Dingledine, R, Gorman, JM, Grigoriadis, DE, Henderson, DC, Innis, RB, Killen, J, Laughren, TP, McDonald, WM, Murphy, GM, Paul, SM, Rudorfer, MV, Sausville, E, Schatzberg, AF, Scolnick, EM & Suppes, T 2002, 'Developing novel treatments for mood disorders: Accelerating discovery', Biological Psychiatry, vol. 52, no. 6, pp. 589-609. https://doi.org/10.1016/S0006-3223(02)01470-1

@article{c7c6adf42729491e9a7d819a5436adbf,

title = "Developing novel treatments for mood disorders: Accelerating discovery",

abstract = "This review was generated from discussions by the Pharmacologic and Somatic Treatments Section of the National Institute of Mental Health Strategic Plan for Mood Disorders Committee on advancing novel pharmacologic and somatic treatments for mood disorders. The opening section of the article summarizes in broad strokes, current pharmacologic treatments, and new directions in the field. Thereafter the topics focus on specific research initiatives that could advance the current therapeutics for mood disorders including new basic and clinical research in vivo human imaging procedures, somatic therapeutics, and the vast new area of pharmacogenetics. New scientific and technical opportunities exist today based on advances in basic neuroscience, opportunities in clinical testing, industry interest in advancing central nervous system therapeutics, and on active consumer advocacy groups. The question of how to bring all of these positive forces together to accelerate discovery in mood disorder therapeutics is the topic of this article.",

keywords = "Depression bipolar disorder research resources, Government/industry collaboration",

author = "Tamminga, {Carol A.} and Nemeroff, {Charles B.} and Blakely, {Randy D.} and Linda Brady and Carter, {Cameron S.} and Davis, {Kenneth L.} and Raymond Dingledine and Gorman, {Jack M.} and Grigoriadis, {Dimitri E.} and Henderson, {David C.} and Innis, {Robert B.} and John Killen and Laughren, {Thomas P.} and McDonald, {William M.} and Murphy, {Greer M.} and Paul, {Steven M.} and Rudorfer, {Matthew V.} and Edward Sausville and Schatzberg, {Alan F.} and Scolnick, {Edward M.} and Trisha Suppes",

year = "2002",

month = sep,

day = "15",

doi = "10.1016/S0006-3223(02)01470-1",

language = "English (US)",

volume = "52",

pages = "589--609",

journal = "Biological Psychiatry",

issn = "0006-3223",

publisher = "Elsevier USA",

number = "6",

}

TY - JOUR

T1 - Developing novel treatments for mood disorders

T2 - Accelerating discovery

AU - Tamminga, Carol A.

AU - Nemeroff, Charles B.

AU - Blakely, Randy D.

AU - Brady, Linda

AU - Carter, Cameron S.

AU - Davis, Kenneth L.

AU - Dingledine, Raymond

AU - Gorman, Jack M.

AU - Grigoriadis, Dimitri E.

AU - Henderson, David C.

AU - Innis, Robert B.

AU - Killen, John

AU - Laughren, Thomas P.

AU - McDonald, William M.

AU - Murphy, Greer M.

AU - Paul, Steven M.

AU - Rudorfer, Matthew V.

AU - Sausville, Edward

AU - Schatzberg, Alan F.

AU - Scolnick, Edward M.

AU - Suppes, Trisha

PY - 2002/9/15

Y1 - 2002/9/15

N2 - This review was generated from discussions by the Pharmacologic and Somatic Treatments Section of the National Institute of Mental Health Strategic Plan for Mood Disorders Committee on advancing novel pharmacologic and somatic treatments for mood disorders. The opening section of the article summarizes in broad strokes, current pharmacologic treatments, and new directions in the field. Thereafter the topics focus on specific research initiatives that could advance the current therapeutics for mood disorders including new basic and clinical research in vivo human imaging procedures, somatic therapeutics, and the vast new area of pharmacogenetics. New scientific and technical opportunities exist today based on advances in basic neuroscience, opportunities in clinical testing, industry interest in advancing central nervous system therapeutics, and on active consumer advocacy groups. The question of how to bring all of these positive forces together to accelerate discovery in mood disorder therapeutics is the topic of this article.

AB - This review was generated from discussions by the Pharmacologic and Somatic Treatments Section of the National Institute of Mental Health Strategic Plan for Mood Disorders Committee on advancing novel pharmacologic and somatic treatments for mood disorders. The opening section of the article summarizes in broad strokes, current pharmacologic treatments, and new directions in the field. Thereafter the topics focus on specific research initiatives that could advance the current therapeutics for mood disorders including new basic and clinical research in vivo human imaging procedures, somatic therapeutics, and the vast new area of pharmacogenetics. New scientific and technical opportunities exist today based on advances in basic neuroscience, opportunities in clinical testing, industry interest in advancing central nervous system therapeutics, and on active consumer advocacy groups. The question of how to bring all of these positive forces together to accelerate discovery in mood disorder therapeutics is the topic of this article.

KW - Depression bipolar disorder research resources

KW - Government/industry collaboration

UR - http://www.scopus.com/inward/record.url?scp=0037106951&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0037106951&partnerID=8YFLogxK

U2 - 10.1016/S0006-3223(02)01470-1

DO - 10.1016/S0006-3223(02)01470-1

M3 - Review article

C2 - 12361670

AN - SCOPUS:0037106951

SN - 0006-3223

VL - 52

SP - 589

EP - 609

JO - Biological Psychiatry

JF - Biological Psychiatry

IS - 6

ER -

Developing novel treatments for mood disorders: Accelerating discovery

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this