@article{b16a6462afce4fd0aaf5b369b87d04bf,
title = "Developing EZH2-targeted therapy for lung cancer",
abstract = "Epigenetic targets are exciting new avenues for cancer drug discovery. Zhang and colleagues have designed the open-source EZH2 inhibitor JQEZ5 and shown antitumor efficacy in vitro and in vivo in preclinical studies in murine and human lung adenocarcinoma models expressing high levels of EZH2.",
author = "Frankel, {Arthur E.} and Xin Liu and Minna, {John D.}",
note = "Funding Information: X. Liu was supported by Welch Foundation research grant I-1790, CPRIT research grant R1119, a Rita Allen Foundation research grant, and NIH grant GM114576. J.D. Minna was supported by NCI SPORE P50CA70907, CTD2N CA176284, and CPRIT RP110708. Publisher Copyright: {\textcopyright} 2016 American Association for Cancer Research.",
year = "2016",
month = sep,
doi = "10.1158/2159-8290.CD-16-0800",
language = "English (US)",
volume = "6",
pages = "949--952",
journal = "Cancer discovery",
issn = "2159-8274",
publisher = "American Association for Cancer Research Inc.",
number = "9",
}